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Wednesday, May 2, 2012
Maybe This Is Why Those in Glass Houses Shouldn't Throw Stones [Art]
Two-Drug Therapy Helped Kids With Type 2 Diabetes
SUNDAY, April 29 (HealthDay News) -- Children with type 2 diabetes may achieve better blood sugar control with a combination of two drugs, metformin and Avandia, than with metformin alone, a new study suggests.
However, Avandia (rosiglitazone) was recently linked to an increased risk of heart attack and stroke, so it may not be the best drug for these young patients, experts say.
"Many kids with type 2 have a rapidly progressive disease requiring early onset of insulin therapy, and current approaches to oral therapy may be inadequate," said lead researcher Dr. Philip Zeitler, a professor of medicine at the University of Colorado, Denver.
Zeitler noted that the choice of Avandia as a companion medication was made in 2002, before the cardiac problems with the drug were known.
"Given the problems with rosiglitazone, we are not recommending it at this time," he said. "However, no problems with rosiglitazone have been noted in [the study participants] to date, though the cohort size is too small for a thorough safety analysis."
The report was published online April 29 in the New England Journal of Medicine, to coincide with a planned presentation of the finding at the Pediatric Academic Societies' annual meeting in Boston. The National Institute of Diabetes and Digestive and Kidney Diseases funded the research.
For the study, almost 700 obese children, aged 10 to 17, with type 2 diabetes were randomly assigned to metformin alone, metformin plus Avandia or metformin along with intensive lifestyle changes in diet and exercise.
Over the course of 46 months, the researchers found that metformin alone did not adequately control blood sugar levels in 51.7 percent of patients. Among those who received metformin and lifestyle changes, 46.6 percent did not have their blood sugar controlled.
However, among those taking metformin and Avandia, blood sugar levels were not well-controlled in only 38.6 percent of patients, the researchers found.
In addition, blood sugar control was harder to achieve in black and Hispanic children, they added.
"Metformin is probably not as effective as we've assumed, and additional treatment approaches are urgently needed in this population of adolescents with a steadily progressive form of diabetes," Zeitler said.
In terms of lifestyle changes, Zeitler isn't sure why they didn't work better. Part of the reason may be tied to children's reluctance to adopt new diet and exercise habits, he said.
Dr. Joel Zonszein, director of the clinical diabetes center at Montefiore Medical Center in New York City, said that "type 2 diabetes in children and adolescents is a calamity, because we don't have any good medications."
Type 2 diabetes in children is particularly aggressive and can lead to heart and liver problems at a very young age, he said.
"It is not surprising that combination is better than mono-therapy," Zonszein said. "We want to be aggressive in treating type 2 diabetes in children, but we have to balance the risk and benefits of these drugs. But, we really don't have good data and good medications to treat children."
Another expert, Dr. Spyros Mezitis, an endocrinologist at Lenox Hill Hospital in New York City, added that "we need a whole new set of studies to see how to treat type 2 diabetes in children."
Dr. David B. Allen, from the department of pediatrics at the University of Wisconsin School of Medicine and Public Health in Madison, said that "calories consumed in excess of expended is leading to an epidemic of early-life type 2 diabetes, the burden of which is falling disproportionately on disadvantaged youth."
This latest study shows that, once children develop the condition, it is very difficult to prevent deterioration in spite of intensive lifestyle changes or medications, he said.
More information
For more on diabetes, visit the U.S. National Library of Medicine.
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Catholic League President Slams Dan Savage as the Ultimate Bully
Catholic League President Bill Donohue is not having any of Dan Savage's apology.
On Friday, the gay rights activist delivered the keynote addresses at the National High School Journalism Conference in Seattle, saying - while making a general point about how Christians look past plenty of passages in the Bible, most notably those promoting slavery - that folks should “learn to ignore the bullshit in the Bible about gay people.”
In response, a handful of students walked out on the speech and Savage has faced criticism from a number of organizations.
Savage has since clarified certain remarks, specifically saying he regrets referring to the students who left his lecture as making a "pansy-ass move," acknowledging this is a form of bullying.
But is he sorry for the message he was trying to send? No.
“If believers can ignore what the Bible says about slavery, they can ignore what the Bible says about homosexuality," Savage has reiterated as the crux of his point.
But none of that is enough for Donohue. He has released a statement that castigates Savage for a "history of making... vile, disgusting and bigoted remarks" and says:
Ironically, Savage’s bullying of Christian students was done in the name of protesting the bullying of homosexuals. When it comes to bullying, Savage has no peer. We hope the Obama administration, which has welcomed him to the White House, takes note.
What do YOU think, THGers? Does Savage owe Christians more of an apology?
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Tuesday, May 1, 2012
Huawei partners with Intel to test TD-LTE interoperability in China
In a classic case of east meets west, Huawei and Intel have joined forces to create an interoperability test lab that will focus on China's homegrown time-division LTE (TD-LTE) network. While the technology runs contrary to the more common frequency-division LTE (FD-LTE), the Chinese brand of 4G is situated to take root in the US under Clearwire's banner. Through its partnership with Huawei, Chipzilla -- a newbie in the smartphone arena -- will be able to engage in end-to-end testing of its mobile equipment and verify its readiness for TD-LTE. For Huawei's part, it plans to use the test lab as a means to court other handset and chipset manufacturers, and hence drive the adoption of TD-LTE. Naturally, we're left wondering the obvious: whether this unique collaboration will bring about Huawei smartphones with Intel Inside. Mum's the word on that one... for now.
Huawei partners with Intel to test TD-LTE interoperability in China originally appeared on Engadget on Tue, 01 May 2012 07:43:00 EDT. Please see our terms for use of feeds.
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Sunday, April 29, 2012
Google Drive ? Another Option for Cloud Storage
Another option for those who need more Cloud storage, Google has just released Google Drive. 5GB is available to all Google users free, and plans allow you to upgrade to up to 16TB. ? With Google Drive, you’ll be able to create and collaborate in real time (it incorporates Google Docs as well), store your [...]
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Nokia experiments with location-based white space services in Cambridge, UK (video)
Following news of the first successful white space trials in Cambridge, UK, Nokia is now touting its research in the area with a demonstration of location-based services for the unlicensed spectrum. Traditionally, proponents of white space usage have positioned this unused portion of the airwaves as a viable, low-cost method of data transmission, but the Nokia folks have now demonstrated its ability to pinpoint one's location with much greater accuracy than either WiFi or cellular networks. Think of it as a counterpoint to NFC, if you will, but in the following clip, we're shown how an individual might move throughout a museum, and as they approach various exhibits, one's smartphone could provide supplemental information for the nearby artifacts. Beyond its use in museums, Nokia also foresees the technology as useful in the retail space, where businesses may provide consumers with promotions as they walk by. Currently, the necessary equipment to make this all possible is much too large to fit within a typical smartphone, but Nokia hypothesizes that the necessary chipsets and industry standards may be in place by 2015. Until then, you can dream of what might be with the following video.
Continue reading Nokia experiments with location-based white space services in Cambridge, UK (video)
Nokia experiments with location-based white space services in Cambridge, UK (video) originally appeared on Engadget on Sat, 28 Apr 2012 09:37:00 EDT. Please see our terms for use of feeds.
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